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Bacillus anthracis GrlA(V96A) Topoisomerase IV, a Quinolone Resistance Mutation That Does Not Affect the Water-Metal Ion Bridge
The rise in quinolone resistance is threatening the clinical use of this important class of broad-spectrum antibacterials. Quinolones kill bacteria by increasing the level of DNA strand breaks generated by the type II topoisomerases gyrase and topoisomerase IV. Most commonly, resistance is caused by...
में बचाया:
| में प्रकाशित: | Antimicrob Agents Chemother |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249509/ https://ncbi.nlm.nih.gov/pubmed/25246407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03734-14 |
| टैग : |
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