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Bacillus anthracis GrlA(V96A) Topoisomerase IV, a Quinolone Resistance Mutation That Does Not Affect the Water-Metal Ion Bridge
The rise in quinolone resistance is threatening the clinical use of this important class of broad-spectrum antibacterials. Quinolones kill bacteria by increasing the level of DNA strand breaks generated by the type II topoisomerases gyrase and topoisomerase IV. Most commonly, resistance is caused by...
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| 發表在: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249509/ https://ncbi.nlm.nih.gov/pubmed/25246407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03734-14 |
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