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Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase

[Image: see text] Mycobacterium tuberculosis encodes only a single type II topoisomerase, gyrase. As a result, this enzyme likely carries out the cellular functions normally performed by canonical gyrase and topoisomerase IV, both in front of and behind the replication fork. In addition, it is the s...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Ashley, Rachel E., Blower, Tim R., Berger, James M., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637011/
https://ncbi.nlm.nih.gov/pubmed/28921956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00681
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