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ABILITY OF VIRAL TOPOISOMERASE II TO DISCERN THE HANDEDNESS OF SUPERCOILED DNA: BIMODAL RECOGNITION OF DNA GEOMETRY BY TYPE II ENZYMES

Previous studies with human and bacterial topoisomerases suggest that the type II enzyme utilizes two distinct mechanisms to recognize the handedness of DNA supercoils. It has been proposed that the ability of some type II enzymes, such as human topoisomerase IIα and Eschericia coli topoisomerase IV...

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שמור ב:
מידע ביבליוגרפי
Main Authors: McClendon, A. Kathleen, Dickey, Jennifer S., Osheroff, Neil
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517260/
https://ncbi.nlm.nih.gov/pubmed/16981727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0520838
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