Interactions between the Etoposide Derivative F14512 and Human Type II Topoisomerases: Implications for the C4 Spermine Moiety in Promoting Enzyme-mediated DNA Cleavage

Por Gentry, Amanda C., Pitts, Steven L., Jablonsky, Michael J., Bailly, Christian, Graves, David E., Osheroff, Neil
Publicado em 2011

Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV

Por Pitts, Steven L., Liou, Grace F., Mitchenall, Lesley A., Burgin, Alex B., Maxwell, Anthony, Neuman, Keir C., Osheroff, Neil
Publicado em 2011

Synthesis and evaluation of ether-linked demethylepipodophyllotoxin dimers

Por Dunlap, Norma, Salyard, Tracy L. J., Pathiranage, Anuradha Liyana, Stubblefield, Jeannie, Pitts, Steven L., Ashley, Rachel E., Osheroff, Neil
Publicado no Bioorg Med Chem Lett (2014)

Contributions of the D-Ring to the Activity of Etoposide Against Human Topoisomerase IIα: Potential Interactions with DNA in the Ternary Enzyme-Drug-DNA Complex

Por Pitts, Steven L., Jablonksy, Michael J., Duca, Maria, Dauzonne, Daniel, Monneret, Claude, Arimondo, Paola B., Anklin, Clemens, Graves, David E., Osheroff, Neil
Publicado em 2011