Natural Products as Topoisomerase II Poisons: Effects of Thymoquinone on DNA Cleavage Mediated by Human Topoisomerase IIα

ανά Ashley, Rachel E., Osheroff, Neil
Έκδοση 2014

Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase

ανά Ashley, Rachel E., Blower, Tim R., Berger, James M., Osheroff, Neil
Τόπος έκδοσης Biochemistry (2017)

Oxidative transformation of demethoxy- and bisdemethoxycurcumin: Products, mechanism of formation, and poisoning of human topoisomerase IIα

ανά Gordon, Odaine N., Luis, Paula B., Ashley, Rachel E., Osheroff, Neil, Schneider, Claus
Τόπος έκδοσης Chem Res Toxicol (2015)

Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism

ανά Lindsey, R. Hunter, Pendleton, MaryJean, Ashley, Rachel E., Mercer, Susan L., Deweese, Joseph E., Osheroff, Neil
Έκδοση 2014

Activities of gyrase and topoisomerase IV on positively supercoiled DNA

ανά Ashley, Rachel E., Dittmore, Andrew, McPherson, Sylvia A., Turnbough, Charles L., Neuman, Keir C., Osheroff, Neil
Τόπος έκδοσης Nucleic Acids Res (2017)

Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance

ανά Ashley, Rachel E., Lindsey, R. Hunter, McPherson, Sylvia A., Turnbough, Charles L., Kerns, Robert J., Osheroff, Neil
Τόπος έκδοσης Biochemistry (2017)

Synthesis and evaluation of ether-linked demethylepipodophyllotoxin dimers

ανά Dunlap, Norma, Salyard, Tracy L. J., Pathiranage, Anuradha Liyana, Stubblefield, Jeannie, Pitts, Steven L., Ashley, Rachel E., Osheroff, Neil
Τόπος έκδοσης Bioorg Med Chem Lett (2014)