Multifactorial, Biomarker-Based Predictive Models for Immunotherapy Response Enter the Arena

by Appleman, Leonard J
Published in J Natl Cancer Inst (2020)

Update on vaccine development for renal cell cancer

by Chi, Nina, Maranchie, Jodi K, Appleman, Leonard J, Storkus, Walter J
Published 2010

The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment

by Parikh, Rahul A, Wang, Peng, Beumer, Jan H, Chu, Edward, Appleman, Leonard J
Published 2014

Radium-223 Therapy for Patients with Metastatic Castrate-Resistant Prostate Cancer: An Update on Literature with Case Presentation

by Nguyen, Nghi C., Shah, Muhammad, Appleman, Leonard J., Parikh, Rahul, Mountz, James M.
Published in Int J Mol Imaging (2016)

Broccoli-Derived Sulforaphane and Chemoprevention of Prostate Cancer: From Bench to Bedside

by Amjad, Ali I., Parikh, Rahul A., Appleman, Leonard J., Hahm, Eun-Ryeong, Singh, Kamayani, Singh, Shivendra V.
Published in Curr Pharmacol Rep (2015)

High-dose interleukin 2 in patients with metastatic renal cell carcinoma with sarcomatoid features

by Achkar, Tala, Arjunan, Ananth, Wang, Hong, Saul, Melissa, Davar, Diwakar, Appleman, Leonard J., Friedland, David, Parikh, Rahul A.
Published in PLoS One (2017)

A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer

by Tolcher, Anthony W., Appleman, Leonard J., Shapiro, Geoffrey I., Mita, Alain C., Cihon, Frank, Mazzu, Arthur, Sundaresan, Pavur R.
Published 2010

Upregulation of the ATR-CHEK1 Pathway in Oral Squamous Cell Carcinomas

by Parikh, Rahul A., Appleman, Leonard J., Bauman, Julie E., Sankunny, Madhav, Lewis, Dale W., Vlad, Anda, Gollin, Susanne M.
Published in Genes Chromosomes Cancer (2013)

DLK1: A Novel Target for Immunotherapeutic Remodeling of the Tumor Blood Vasculature

by Chi Sabins, Nina, Taylor, Jennifer L, Fabian, Kellsye PL, Appleman, Leonard J, Maranchie, Jodi K, Stolz, Donna Beer, Storkus, Walter J
Published 2013

Renal Medullary Carcinoma: Case Report of an Aggressive Malignancy with Near-Complete Response to Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin Chemotherapy

by Amjad, Ali Imran, Ali, Hira, Appleman, Leonard J., Maranchie, Jodi, Jackman, Stephen, Parwani, Anil, Dhir, Rajiv, Roy, Somak, Parikh, Rahul A.
Published 2014

Phase I and pharmacokinetic study of dasatinib and cetuximab in patients with advanced solid malignancies

by Argiris, Athanassios, Feinstein, Trevor M., Wang, Lin, Yang, Tianbing, Agrawal, Shruti, Appleman, Leonard J., Stoller, Ronald G., Grandis, Jennifer R., Egloff, Ann Marie
Published 2011

Phase I Trial of Belinostat in Combination with 13-cis-Retinoic Acid in Advanced Solid Tumor Malignancies: A California Cancer Consortium NCI/CTEP Sponsored Trial.

by Luu, Thehang, Frankel, Paul, Beumer, Jan H, Lim, Dean, Cristea, Mihaela, Appleman, Leonard J, Lenz, Heinz J, Gandara, David R, Kiesel, Brian F, Piekarz, Richard L, Newman, Edward M
Published in Cancer Chemother Pharmacol (2019)

Tumor mutational load and immune parameters across metastatic Renal Cell Carcinoma (mRCC) risk groups

by de Velasco, Guillermo, Miao, Diana, Voss, Martin H., Hakimi, A. Ari, Hsieh, James J., Tannir, Nizar M., Tamboli, Pheroze, Appleman, Leonard J., Rathmell, W. Kimryn, Van Allen, Eliezer M., Choueiri, Toni K.
Published in Cancer Immunol Res (2016)

A Phase 1, Open–label Study of Trebananib Combined With Sorafenib or Sunitinib in Patients With Advanced Renal Cell Carcinoma

by Hong, David S., Gordon, Michael S., Samlowski, Wolfram E., Kurzrock, Razelle, Tannir, Nizar, Friedland, David, Mendelson, David S., Vogelzang, Nicholas J., Rasmussen, Erik, Wu, Benjamin M., Bass, Michael B., Zhong, Zhandong D., Friberg, Gregory, Appleman, Leonard J.
Published in Clin Genitourin Cancer (2013)

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial

by Escudier, Bernard, Powles, Thomas, Motzer, Robert J., Olencki, Thomas, Arén Frontera, Osvaldo, Oudard, Stephane, Rolland, Frederic, Tomczak, Piotr, Castellano, Daniel, Appleman, Leonard J., Drabkin, Harry, Vaena, Daniel, Milwee, Steven, Youkstetter, Jillian, Lougheed, Julie C., Bracarda, Sergio, Choueiri, Toni K.
Published in J Clin Oncol (2018)

Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma

by Koshkin, Vadim S., Barata, Pedro C., Zhang, Tian, George, Daniel J., Atkins, Michael B., Kelly, William J., Vogelzang, Nicholas J., Pal, Sumanta K., Hsu, JoAnn, Appleman, Leonard J., Ornstein, Moshe C., Gilligan, Timothy, Grivas, Petros, Garcia, Jorge A., Rini, Brian I.
Published in J Immunother Cancer (2018)

A Phase I Study of DMS612, a Novel Bi-functional Alkylating Agent

by Appleman, Leonard J., Balasubramaniam, Sanjeeve, Parise, Robert A, Bryla, Christine, Redon, Christophe E., Nakamura, Asako J., Bonner, William M., Wright, John J, Piekarz, Richard, Kohler, David R, Jiang, Yixing, Belani, Chandra P., Eiseman, Julie, Chu, Edward, Beumer, Jan H., Bates, Susan E.
Published in Clin Cancer Res (2014)

Molecular Subtypes Improve Prognostic Value of International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Model

by de Velasco, Guillermo, Culhane, Aedín C., Fay, André P., Hakimi, A. Ari, Voss, Martin H., Tannir, Nizar M., Tamboli, Pheroze, Appleman, Leonard J., Bellmunt, Joaquim, Kimryn Rathmell, W., Albiges, Laurence, Hsieh, James J., Heng, Daniel Y. C., Signoretti, Sabina, Choueiri, Toni K.
Published in Oncologist (2017)

Phase 2 Trial of Linifanib (ABT-869) in Patients with Advanced Renal Cell Cancer (RCC) after Sunitinib Failure

by Tannir, Nizar M., Wong, Yu-Ning, Kollmannsberger, Christian K., Ernstoff, Marc S., Perry, David J., Appleman, Leonard J., Posadas, Edwin M., Cho, Daniel, Choueiri, Toni K., Coates, Andrew, Gupta, Neeraj, Pradhan, Rajendra, Qian, Jiang, Chen, Jihong, Scappaticci, Frank A., Ricker, Justin L., Carlson, Dawn M., Michaelson, M. Dror
Published 2011

Neoadjuvant Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With Pegfilgrastim Support in Muscle-Invasive Urothelial Cancer: Pathologic, Radiologic, and Biomarker...

by Choueiri, Toni K., Jacobus, Susanna, Bellmunt, Joaquim, Qu, Angela, Appleman, Leonard J., Tretter, Christopher, Bubley, Glenn J., Stack, Edward C., Signoretti, Sabina, Walsh, Meghara, Steele, Graeme, Hirsch, Michelle, Sweeney, Christopher J., Taplin, Mary-Ellen, Kibel, Adam S., Krajewski, Katherine M., Kantoff, Philip W., Ross, Robert W., Rosenberg, Jonathan E.
Published in J Clin Oncol (2014)