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The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment

MET is located on chromosome 7q31 and is a proto-oncogene that encodes for hepatocyte growth factor (HGF) receptor, a member of the receptor tyrosine kinase (RTK) family. HGF, also known as scatter factor (SF), is the only known ligand for MET. MET is a master regulator of cell growth and division (...

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Detalhes bibliográficos
Main Authors: Parikh, Rahul A, Wang, Peng, Beumer, Jan H, Chu, Edward, Appleman, Leonard J
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061161/
https://ncbi.nlm.nih.gov/pubmed/24959084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S40241
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