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Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma

Glioblastoma (GBM) is a lethal brain tumor with dismal prognosis. Current therapeutic options, consisting of surgery, chemotherapy and radiation, have only served to marginally increase patient survival. Receptor tyrosine kinases (RTKs) are dysregulated in approximately 90% of GBM; attributed to thi...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Cruickshanks, Nichola, Zhang, Ying, Yuan, Fang, Pahuski, Mary, Gibert, Myron, Abounader, Roger
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532623/
https://ncbi.nlm.nih.gov/pubmed/28696366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9070087
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