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Targeting the HGF/MET signalling pathway in cancer therapy

INTRODUCTION: Under normal conditions, hepatocyte growth factor (HGF)-induced activation of its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand delivery, ligand activation at the target cell surface, and ligand activated receptor internalization and degr...

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Detalhes bibliográficos
Main Authors: Cecchi, Fabiola, Rabe, Daniel C., Bottaro, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711667/
https://ncbi.nlm.nih.gov/pubmed/22530990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2012.680957
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