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Targeting the HGF/Met Signaling Pathway in Cancer

Under normal conditions, hepatocyte growth factor (HGF)-induced Met tyrosine kinase (TK) activation is tightly regulated by paracrine ligand delivery, ligand activation at the target cell surface, and ligand activated receptor internalization and degradation. Despite these controls, HGF/Met signalin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cecchi, Fabiola, Rabe, Daniel C., Bottaro, Donald P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412517/
https://ncbi.nlm.nih.gov/pubmed/20303741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.02.028
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