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Targeting the HGF/Met Signaling Pathway in Cancer

Under normal conditions, hepatocyte growth factor (HGF)-induced Met tyrosine kinase (TK) activation is tightly regulated by paracrine ligand delivery, ligand activation at the target cell surface, and ligand activated receptor internalization and degradation. Despite these controls, HGF/Met signalin...

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Detalhes bibliográficos
Main Authors: Cecchi, Fabiola, Rabe, Daniel C., Bottaro, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412517/
https://ncbi.nlm.nih.gov/pubmed/20303741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.02.028
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