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Targeting the HGF/Met Signaling Pathway in Cancer
Under normal conditions, hepatocyte growth factor (HGF)-induced Met tyrosine kinase (TK) activation is tightly regulated by paracrine ligand delivery, ligand activation at the target cell surface, and ligand activated receptor internalization and degradation. Despite these controls, HGF/Met signalin...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412517/ https://ncbi.nlm.nih.gov/pubmed/20303741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.02.028 |
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