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The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in Cancer
Under normal conditions, hepatocyte growth factor (HGF)-induced activation of its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand delivery, ligand activation at the target cell surface, and ligand activated receptor internalization and degradation. Despi...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156285/ https://ncbi.nlm.nih.gov/pubmed/25197268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157436211795659955 |
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