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The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in Cancer

Under normal conditions, hepatocyte growth factor (HGF)-induced activation of its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand delivery, ligand activation at the target cell surface, and ligand activated receptor internalization and degradation. Despi...

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Detalhes bibliográficos
Main Authors: Cecchi, Fabiola, Rabe, Daniel C., Bottaro, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156285/
https://ncbi.nlm.nih.gov/pubmed/25197268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157436211795659955
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