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Discovery and therapeutic exploitation of mechanisms of resistance to MET inhibitors in glioblastoma
PURPOSE: Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or over activated in GBM. Although clinically applicable MET inhibitors have been developed, resistance to single modality anti-MET drugs frequentl...
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| Publicado no: | Clin Cancer Res |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6335175/ https://ncbi.nlm.nih.gov/pubmed/30201763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0926 |
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