טוען...

Discovery and therapeutic exploitation of mechanisms of resistance to MET inhibitors in glioblastoma

PURPOSE: Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or over activated in GBM. Although clinically applicable MET inhibitors have been developed, resistance to single modality anti-MET drugs frequentl...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Cancer Res
Main Authors: Cruickshanks, Nichola, Zhang, Ying, Hine, Sarah, Gibert, Myron, Yuan, Fang, Oxford, Madison, Grello, Cassandra, Pahuski, Mary, Dube, Collin, Guessous, Fadila, Wang, Baomin, Deveau, Ciana, Saoud, Karim, Gallagher, Isela, Wulfkuhle, Julia, Schiff, David, Phan, See, Petricoin, Emanuel, Abounader, Roger
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335175/
https://ncbi.nlm.nih.gov/pubmed/30201763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0926
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