Multifactorial, Biomarker-Based Predictive Models for Immunotherapy Response Enter the Arena

Por Appleman, Leonard J
Publicado no J Natl Cancer Inst (2020)

Update on vaccine development for renal cell cancer

Por Chi, Nina, Maranchie, Jodi K, Appleman, Leonard J, Storkus, Walter J
Publicado em 2010

The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment

Por Parikh, Rahul A, Wang, Peng, Beumer, Jan H, Chu, Edward, Appleman, Leonard J
Publicado em 2014

Radium-223 Therapy for Patients with Metastatic Castrate-Resistant Prostate Cancer: An Update on Literature with Case Presentation

Por Nguyen, Nghi C., Shah, Muhammad, Appleman, Leonard J., Parikh, Rahul, Mountz, James M.
Publicado no Int J Mol Imaging (2016)

Broccoli-Derived Sulforaphane and Chemoprevention of Prostate Cancer: From Bench to Bedside

Por Amjad, Ali I., Parikh, Rahul A., Appleman, Leonard J., Hahm, Eun-Ryeong, Singh, Kamayani, Singh, Shivendra V.
Publicado no Curr Pharmacol Rep (2015)

High-dose interleukin 2 in patients with metastatic renal cell carcinoma with sarcomatoid features

Por Achkar, Tala, Arjunan, Ananth, Wang, Hong, Saul, Melissa, Davar, Diwakar, Appleman, Leonard J., Friedland, David, Parikh, Rahul A.
Publicado no PLoS One (2017)

A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer

Por Tolcher, Anthony W., Appleman, Leonard J., Shapiro, Geoffrey I., Mita, Alain C., Cihon, Frank, Mazzu, Arthur, Sundaresan, Pavur R.
Publicado em 2010

Upregulation of the ATR-CHEK1 Pathway in Oral Squamous Cell Carcinomas

Por Parikh, Rahul A., Appleman, Leonard J., Bauman, Julie E., Sankunny, Madhav, Lewis, Dale W., Vlad, Anda, Gollin, Susanne M.
Publicado no Genes Chromosomes Cancer (2013)

DLK1: A Novel Target for Immunotherapeutic Remodeling of the Tumor Blood Vasculature

Por Chi Sabins, Nina, Taylor, Jennifer L, Fabian, Kellsye PL, Appleman, Leonard J, Maranchie, Jodi K, Stolz, Donna Beer, Storkus, Walter J
Publicado em 2013

Renal Medullary Carcinoma: Case Report of an Aggressive Malignancy with Near-Complete Response to Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin Chemotherapy

Por Amjad, Ali Imran, Ali, Hira, Appleman, Leonard J., Maranchie, Jodi, Jackman, Stephen, Parwani, Anil, Dhir, Rajiv, Roy, Somak, Parikh, Rahul A.
Publicado em 2014

Phase I and pharmacokinetic study of dasatinib and cetuximab in patients with advanced solid malignancies

Por Argiris, Athanassios, Feinstein, Trevor M., Wang, Lin, Yang, Tianbing, Agrawal, Shruti, Appleman, Leonard J., Stoller, Ronald G., Grandis, Jennifer R., Egloff, Ann Marie
Publicado em 2011

Phase I Trial of Belinostat in Combination with 13-cis-Retinoic Acid in Advanced Solid Tumor Malignancies: A California Cancer Consortium NCI/CTEP Sponsored Trial.

Por Luu, Thehang, Frankel, Paul, Beumer, Jan H, Lim, Dean, Cristea, Mihaela, Appleman, Leonard J, Lenz, Heinz J, Gandara, David R, Kiesel, Brian F, Piekarz, Richard L, Newman, Edward M
Publicado no Cancer Chemother Pharmacol (2019)

Tumor mutational load and immune parameters across metastatic Renal Cell Carcinoma (mRCC) risk groups

Por de Velasco, Guillermo, Miao, Diana, Voss, Martin H., Hakimi, A. Ari, Hsieh, James J., Tannir, Nizar M., Tamboli, Pheroze, Appleman, Leonard J., Rathmell, W. Kimryn, Van Allen, Eliezer M., Choueiri, Toni K.
Publicado no Cancer Immunol Res (2016)

A Phase 1, Open–label Study of Trebananib Combined With Sorafenib or Sunitinib in Patients With Advanced Renal Cell Carcinoma

Por Hong, David S., Gordon, Michael S., Samlowski, Wolfram E., Kurzrock, Razelle, Tannir, Nizar, Friedland, David, Mendelson, David S., Vogelzang, Nicholas J., Rasmussen, Erik, Wu, Benjamin M., Bass, Michael B., Zhong, Zhandong D., Friberg, Gregory, Appleman, Leonard J.
Publicado no Clin Genitourin Cancer (2013)

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial

Por Escudier, Bernard, Powles, Thomas, Motzer, Robert J., Olencki, Thomas, Arén Frontera, Osvaldo, Oudard, Stephane, Rolland, Frederic, Tomczak, Piotr, Castellano, Daniel, Appleman, Leonard J., Drabkin, Harry, Vaena, Daniel, Milwee, Steven, Youkstetter, Jillian, Lougheed, Julie C., Bracarda, Sergio, Choueiri, Toni K.
Publicado no J Clin Oncol (2018)

Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma

Por Koshkin, Vadim S., Barata, Pedro C., Zhang, Tian, George, Daniel J., Atkins, Michael B., Kelly, William J., Vogelzang, Nicholas J., Pal, Sumanta K., Hsu, JoAnn, Appleman, Leonard J., Ornstein, Moshe C., Gilligan, Timothy, Grivas, Petros, Garcia, Jorge A., Rini, Brian I.
Publicado no J Immunother Cancer (2018)

A Phase I Study of DMS612, a Novel Bi-functional Alkylating Agent

Por Appleman, Leonard J., Balasubramaniam, Sanjeeve, Parise, Robert A, Bryla, Christine, Redon, Christophe E., Nakamura, Asako J., Bonner, William M., Wright, John J, Piekarz, Richard, Kohler, David R, Jiang, Yixing, Belani, Chandra P., Eiseman, Julie, Chu, Edward, Beumer, Jan H., Bates, Susan E.
Publicado no Clin Cancer Res (2014)

Molecular Subtypes Improve Prognostic Value of International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Model

Por de Velasco, Guillermo, Culhane, Aedín C., Fay, André P., Hakimi, A. Ari, Voss, Martin H., Tannir, Nizar M., Tamboli, Pheroze, Appleman, Leonard J., Bellmunt, Joaquim, Kimryn Rathmell, W., Albiges, Laurence, Hsieh, James J., Heng, Daniel Y. C., Signoretti, Sabina, Choueiri, Toni K.
Publicado no Oncologist (2017)

Phase 2 Trial of Linifanib (ABT-869) in Patients with Advanced Renal Cell Cancer (RCC) after Sunitinib Failure

Por Tannir, Nizar M., Wong, Yu-Ning, Kollmannsberger, Christian K., Ernstoff, Marc S., Perry, David J., Appleman, Leonard J., Posadas, Edwin M., Cho, Daniel, Choueiri, Toni K., Coates, Andrew, Gupta, Neeraj, Pradhan, Rajendra, Qian, Jiang, Chen, Jihong, Scappaticci, Frank A., Ricker, Justin L., Carlson, Dawn M., Michaelson, M. Dror
Publicado em 2011

Neoadjuvant Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With Pegfilgrastim Support in Muscle-Invasive Urothelial Cancer: Pathologic, Radiologic, and Biomarker...

Por Choueiri, Toni K., Jacobus, Susanna, Bellmunt, Joaquim, Qu, Angela, Appleman, Leonard J., Tretter, Christopher, Bubley, Glenn J., Stack, Edward C., Signoretti, Sabina, Walsh, Meghara, Steele, Graeme, Hirsch, Michelle, Sweeney, Christopher J., Taplin, Mary-Ellen, Kibel, Adam S., Krajewski, Katherine M., Kantoff, Philip W., Ross, Robert W., Rosenberg, Jonathan E.
Publicado no J Clin Oncol (2014)