DLK1: A Novel Target for Immunotherapeutic Remodeling of the Tumor Blood Vasculature

Tumor blood vessels are frequently inefficient in their design and function, leading to high interstitial fluid pressure, hypoxia, and acidosis in the tumor microenvironment (TME), rendering tumors refractory to the delivery of chemotherapeutic agents and immune effector cells. Here we identified th...

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Detalhes bibliográficos
Main Authors: Chi Sabins, Nina, Taylor, Jennifer L, Fabian, Kellsye PL, Appleman, Leonard J, Maranchie, Jodi K, Stolz, Donna Beer, Storkus, Walter J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808139/
https://ncbi.nlm.nih.gov/pubmed/23896726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.133
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