Mutagenesis of the NS2B-NS3-Mediated Cleavage Site in the Flavivirus Capsid Protein Demonstrates a Requirement for Coordinated Processing

Por Amberg, Sean M., Rice, Charles M.
Publicado em 1999

Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication.

Por Chambers, T J, Nestorowicz, A, Amberg, S M, Rice, C M
Publicado em 1993

Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site.

Por Lin, C, Amberg, S M, Chambers, T J, Rice, C M
Publicado em 1993

Expanded Tropism and Altered Activation of a Retroviral Glycoprotein Resistant to an Entry Inhibitor Peptide

Por Amberg, Sean M., Netter, Robert C., Simmons, Graham, Bates, Paul
Publicado em 2006

pH-Induced Activation of Arenavirus Membrane Fusion Is Antagonized by Small-Molecule Inhibitors

Por York, Joanne, Dai, Dongcheng, Amberg, Sean M., Nunberg, Jack H.
Publicado em 2008

NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies.

Por Amberg, S M, Nestorowicz, A, McCourt, D W, Rice, C M
Publicado em 1994

Mutagenesis of the Signal Sequence of Yellow Fever Virus prM Protein: Enhancement of Signalase Cleavage In Vitro Is Lethal for Virus Production

Por Lee, Eva, Stocks, Christine E., Amberg, Sean M., Rice, Charles M., Lobigs, Mario
Publicado em 2000

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

Por Simmons, Graham, Reeves, Jacqueline D., Rennekamp, Andrew J., Amberg, Sean M., Piefer, Andrew J., Bates, Paul
Publicado em 2004

Identification of a Broad-Spectrum Arenavirus Entry Inhibitor

Por Larson, Ryan A., Dai, Dongcheng, Hosack, Virginia T., Tan, Ying, Bolken, Tove’ C., Hruby, Dennis E., Amberg, Sean M.
Publicado em 2008

Heptad Repeat 2-Based Peptides Inhibit Avian Sarcoma and Leukosis Virus Subgroup A Infection and Identify a Fusion Intermediate

Por Netter, Robert C., Amberg, Sean M., Balliet, John W., Biscone, Mark J., Vermeulen, Arwen, Earp, Laurie J., White, Judith M., Bates, Paul
Publicado em 2004

Lead optimization of an acylhydrazone scaffold possessing antiviral activity against Lassa virus

Por Burgeson, James R., Gharaibeh, Dima N., Moore, Amy L., Larson, Ryan A., Amberg, Sean M., Bolken, Tove’ C., Hruby, Dennis E., Dai, Dongcheng
Publicado em 2013

Inhibitors of SARS-CoV entry – Identification using an internally-controlled dual envelope pseudovirion assay

Por Zhou, Yanchen, Agudelo, Juliet, Lu, Kai, Goetz, David H., Hansell, Elizabeth, Chen, Yen Ting, Roush, William R., McKerrow, James, Craik, Charles S., Amberg, Sean M., Simmons, Graham
Publicado em 2011

A Specific Interaction of Small Molecule Entry Inhibitors with the Envelope Glycoprotein Complex of the Junín Hemorrhagic Fever Arenavirus

Por Thomas, Celestine J., Casquilho-Gray, Hedi E., York, Joanne, DeCamp, Dianne L., Dai, Dongcheng, Petrilli, Erin B., Boger, Dale L., Slayden, Richard A., Amberg, Sean M., Sprang, Stephen R., Nunberg, Jack H.
Publicado em 2011

Evaluation of Lassa antiviral compound ST-193 in a guinea pig model

Por Cashman, Kathleen A., Smith, Mark A., Twenhafel, Nancy A., Larson, Ryan A., Jones, Kevin F., Allen, Robert D., Dai, Dongcheng, Chinsangaram, Jarasvech, Bolken, Tove’ C., Hruby, Dennis E., Amberg, Sean M., Hensley, Lisa E., Guttieri, Mary C.
Publicado em 2011