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Expanded Tropism and Altered Activation of a Retroviral Glycoprotein Resistant to an Entry Inhibitor Peptide

The envelope of class I viruses can be a target for potent viral inhibitors, such as the human immunodeficiency virus type 1 (HIV-1) inhibitor enfuvirtide, which are derived from the C-terminal heptad repeat (HR2) of the transmembrane (TM) subunit. Resistance to an HR2-based peptide inhibitor of a m...

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Detalhes bibliográficos
Main Authors: Amberg, Sean M., Netter, Robert C., Simmons, Graham, Bates, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317511/
https://ncbi.nlm.nih.gov/pubmed/16352560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.353-359.2006
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