Identification of a Broad-Spectrum Arenavirus Entry Inhibitor

Several arenaviruses, including Lassa virus (LASV), are causative agents of hemorrhagic fever, for which effective therapeutic options are lacking. The LASV envelope glycoprotein (GP) gene was used to generate lentiviral pseudotypes to identify small-molecule inhibitors of viral entry. A benzimidazo...

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Bibliografiska uppgifter
Huvudupphovsmän: Larson, Ryan A., Dai, Dongcheng, Hosack, Virginia T., Tan, Ying, Bolken, Tove’ C., Hruby, Dennis E., Amberg, Sean M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573164/
https://ncbi.nlm.nih.gov/pubmed/18715909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00941-08
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