Identification of a Broad-Spectrum Arenavirus Entry Inhibitor

Several arenaviruses, including Lassa virus (LASV), are causative agents of hemorrhagic fever, for which effective therapeutic options are lacking. The LASV envelope glycoprotein (GP) gene was used to generate lentiviral pseudotypes to identify small-molecule inhibitors of viral entry. A benzimidazo...

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Detalhes bibliográficos
Main Authors: Larson, Ryan A., Dai, Dongcheng, Hosack, Virginia T., Tan, Ying, Bolken, Tove’ C., Hruby, Dennis E., Amberg, Sean M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573164/
https://ncbi.nlm.nih.gov/pubmed/18715909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00941-08
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