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Peptide Inhibitors of Flavivirus Entry Derived from the E Protein Stem

Peptides derived from the “stem” of dengue virus (DV) type 2 (DV2) envelope (E) protein inhibit DV2 infectivity, targeting a late-stage fusion intermediate. We show here that stem peptides from all DV serotypes cross-inhibit DV1 to DV4 but that corresponding peptides derived from related flaviviruse...

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Autori principali: Schmidt, Aaron G., Yang, Priscilla L., Harrison, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004314/
https://ncbi.nlm.nih.gov/pubmed/20881042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01440-10
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