A Specific Interaction of Small Molecule Entry Inhibitors with the Envelope Glycoprotein Complex of the Junín Hemorrhagic Fever Arenavirus

Arenaviruses are responsible for acute hemorrhagic fevers worldwide and are recognized to pose significant threats to public health and biodefense. Small molecule compounds have recently been discovered that inhibit arenavirus entry and protect against lethal infection in animal models. These chemic...

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Autores principales: Thomas, Celestine J., Casquilho-Gray, Hedi E., York, Joanne, DeCamp, Dianne L., Dai, Dongcheng, Petrilli, Erin B., Boger, Dale L., Slayden, Richard A., Amberg, Sean M., Sprang, Stephen R., Nunberg, Jack H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057843/
https://ncbi.nlm.nih.gov/pubmed/21159779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196428
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