SAR Studies of Diphenyl Cationic Trypanocides: Superior Activity of Phosphonium over Ammonium Salts

Por Dardonville, Christophe, Alkhaldi, Abdulsalam A. M., De Koning, Harry P.
Publicado no ACS Med Chem Lett (2014)

Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma brucei

Por Alkhaldi, Abdulsalam A.M., Martinek, Jan, Panicucci, Brian, Dardonville, Christophe, Zíková, Alena, de Koning, Harry P.
Publicado no Int J Parasitol Drugs Drug Resist (2015)

Symmetrical choline-derived dications display strong anti-kinetoplastid activity

Por Ibrahim, Hasan M. S., Al-Salabi, Mohammed I., El Sabbagh, Nasser, Quashie, Neils B., Alkhaldi, Abdulsalam A. M., Escale, Roger, Smith, Terry K., Vial, Henri J., de Koning, Harry P.
Publicado em 2011

Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy

Por Rodenko, Boris, Wanner, Martin J., Alkhaldi, Abdulsalam A. M., Ebiloma, Godwin U., Barnes, Rebecca L., Kaiser, Marcel, Brun, Reto, McCulloch, Richard, Koomen, Gerrit-Jan, de Koning, Harry P.
Publicado no Antimicrob Agents Chemother (2015)

Functional analysis of drug resistance‐associated mutations in the T rypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein

Por Munday, Jane C., Tagoe, Daniel N. A., Eze, Anthonius A., Krezdorn, Jessica A. M., Rojas López, Karla E., Alkhaldi, Abdulsalam A. M., McDonald, Fiona, Still, Jennifer, Alzahrani, Khalid J., Settimo, Luca, De Koning, Harry P.
Publicado no Mol Microbiol (2015)