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Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma brucei
Lipophilic bisphosphonium salts are among the most promising antiprotozoal leads currently under investigation. As part of their preclinical evaluation we here report on their mode of action against African trypanosomes, the etiological agents of sleeping sickness. The bisphosphonium compounds CD38...
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Publicado no: | Int J Parasitol Drugs Drug Resist |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805778/ https://ncbi.nlm.nih.gov/pubmed/27054061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.12.002 |
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