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Pyrimidine Salvage in Trypanosoma brucei Bloodstream Forms and the Trypanocidal Action of Halogenated Pyrimidiness

African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host. However, uptake of pyrimidines in bloodstream form trypanosomes has not been investigated, making it difficult to judge the relative importance of salvage and synthesis or to design a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Pharmacol
Prif Awduron: Ali, Juma A. M., Creek, Darren J., Burgess, Karl, Allison, Harriet C., Field, Mark C., Mäser, Pascal, De Koning, Harry P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857052/
https://ncbi.nlm.nih.gov/pubmed/23188714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.082321
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