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Halogenated tryptophan derivatives disrupt essential transamination mechanisms in bloodstream form Trypanosoma brucei

Amino acid metabolism within Trypanosoma brucei, the causative agent of human African trypanosomiasis, is critical for parasite survival and virulence. Of these metabolic processes, the transamination of aromatic amino acids is one of the most important. In this study, a series of halogenated trypto...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Cockram, Peter E., Dickie, Emily A., Barrett, Michael P., Smith, Terry K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744056/
https://ncbi.nlm.nih.gov/pubmed/33275612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008928
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