Typhoid Fever Diagnosis in Endemic Countries: A Clog in the Wheel of Progress?

Por Ajibola, Olumide, Mshelia, Mari B., Gulumbe, Bashar H., Eze, Anthonius A.
Publicado no Medicina (Kaunas) (2018)

The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

Por Eze, Anthonius A., Igoli, John, Gray, Alexander I., Skellern, Graham G., De Koning, Harry P.
Publicado no Int J Parasitol Drugs Drug Resist (2019)

Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F(1)F(o)-ATPase

Por Eze, Anthonius A., Gould, Matthew K., Munday, Jane C., Tagoe, Daniel N. A., Stelmanis, Valters, Schnaufer, Achim, De Koning, Harry P.
Publicado no PLoS Negl Trop Dis (2016)

Urogenital schistosomiasis is associated with signatures of microbiome dysbiosis in Nigerian adolescents

Por Ajibola, Olumide, Rowan, Aislinn D., Ogedengbe, Clement O., Mshelia, Mari B., Cabral, Damien J., Eze, Anthonius A., Obaro, Stephen, Belenky, Peter
Publicado no Sci Rep (2019)

Monotherapy with amlodipine or hydrochlorothiazide in patients with mild to moderate hypertension: Comparison of their efficacy and effects on electrolytes

Por Nwachukwu, Daniel C, Eze, Anthonius A, Nwachukwu, Nkiru Z, Aneke, Eddy I, Agu, Polycarp U, Azubike, Nkiru C, Obika, Leonard FO, Okoye, Onochie I
Publicado no Malawi Med J (2017)

A New Nonpolar N-Hydroxy Imidazoline Lead Compound with Improved Activity in a Murine Model of Late-Stage Trypanosoma brucei brucei Infection Is Not Cross-Resistant with Diamidines

Por Ríos Martínez, Carlos H., Miller, Florence, Ganeshamoorthy, Kayathiri, Glacial, Fabienne, Kaiser, Marcel, de Koning, Harry P., Eze, Anthonius A., Lagartera, Laura, Herraiz, Tomás, Dardonville, Christophe
Publicado no Antimicrob Agents Chemother (2015)

Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake()

Por Munday, Jane C., Rojas López, Karla E., Eze, Anthonius A., Delespaux, Vincent, Van Den Abbeele, Jan, Rowan, Tim, Barrett, Michael P., Morrison, Liam J., de Koning, Harry P.
Publicado em 2013

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

Por Alzahrani, Khalid J.H., Ali, Juma A.M., Eze, Anthonius A., Looi, Wan Limm, Tagoe, Daniel N.A., Creek, Darren J., Barrett, Michael P., de Koning, Harry P.
Publicado no Int J Parasitol Drugs Drug Resist (2017)

The Diamidine Diminazene Aceturate Is a Substrate for the High-Affinity Pentamidine Transporter: Implications for the Development of High Resistance Levels in Trypanosomes

Por Teka, Ibrahim A., Kazibwe, Anne J. N., El-Sabbagh, Nasser, Al-Salabi, Mohammed I., Ward, Christopher P., Eze, Anthonius A., Munday, Jane C., Mäser, Pascal, Matovu, Enock, Barrett, Michael P., de Koning, Harry P.
Publicado em 2011

Functional analysis of drug resistance‐associated mutations in the T rypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein

Por Munday, Jane C., Tagoe, Daniel N. A., Eze, Anthonius A., Krezdorn, Jessica A. M., Rojas López, Karla E., Alkhaldi, Abdulsalam A. M., McDonald, Fiona, Still, Jennifer, Alzahrani, Khalid J., Settimo, Luca, De Koning, Harry P.
Publicado no Mol Microbiol (2015)

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

Por Munday, Jane C., Eze, Anthonius A., Baker, Nicola, Glover, Lucy, Clucas, Caroline, Aguinaga Andrés, David, Natto, Manal J., Teka, Ibrahim A., McDonald, Jennifer, Lee, Rebecca S., Graf, Fabrice E., Ludin, Philipp, Burchmore, Richard J. S., Turner, C. Michael R., Tait, Andy, MacLeod, Annette, Mäser, Pascal, Barrett, Michael P., Horn, David, De Koning, Harry P.
Publicado em 2014

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

Por Alghamdi, Ali H, Munday, Jane C, Campagnaro, Gustavo Daniel, Gurvic, Dominik, Svensson, Fredrik, Okpara, Chinyere E, Kumar, Arvind, Quintana, Juan, Martin Abril, Maria Esther, Milić, Patrik, Watson, Laura, Paape, Daniel, Settimo, Luca, Dimitriou, Anna, Wielinska, Joanna, Smart, Graeme, Anderson, Laura F, Woodley, Christopher M, Kelly, Siu Pui Ying, Ibrahim, Hasan MS, Hulpia, Fabian, Al-Salabi, Mohammed I, Eze, Anthonius A, Sprenger, Teresa, Teka, Ibrahim A, Gudin, Simon, Weyand, Simone, Field, Mark, Dardonville, Christophe, Tidwell, Richard R, Carrington, Mark, O'Neill, Paul, Boykin, David W, Zachariae, Ulrich, De Koning, Harry P
Publicado no eLife (2020)