The Diamidine Diminazene Aceturate Is a Substrate for the High-Affinity Pentamidine Transporter: Implications for the Development of High Resistance Levels in Trypanosomes

African trypanosomiasis is a disease of humans and livestock in many areas south of the Sahara. Resistance to the few existing drugs is a major impediment to the control of these diseases, and we investigated how resistance to the main veterinary drug diminazene aceturate correlates with changes in...

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Главные авторы: Teka, Ibrahim A., Kazibwe, Anne J. N., El-Sabbagh, Nasser, Al-Salabi, Mohammed I., Ward, Christopher P., Eze, Anthonius A., Munday, Jane C., Mäser, Pascal, Matovu, Enock, Barrett, Michael P., de Koning, Harry P.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127539/
https://ncbi.nlm.nih.gov/pubmed/21436312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.071555
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