How Metal Substitution Affects the Enzymatic Activity of Catechol-O-Methyltransferase

Por Sparta, Manuel, Alexandrova, Anastassia N.
Publicado em 2012

Origin of the Activity Drop with the E50D Variant of Catalytic Antibody 34E4 for Kemp Elimination

Por Alexandrova, Anastassia N., Jorgensen, William L.
Publicado em 2009

Why Urea Eliminates Ammonia Rather Than Hydrolyzes in Aqueous Solution

Por Alexandrova, Anastassia N., Jorgensen, William L.
Publicado em 2007

On the Mechanism and Rate of Spontaneous Decomposition of Amino Acids

Por Alexandrova, Anastassia N., Jorgensen, William L.
Publicado em 2011

Rigid substructure search

Por Shirvanyants, David, Alexandrova, Anastassia N., Dokholyan, Nikolay V.
Publicado em 2011

Polarization Effects for Hydrogen-Bonded Complexes of Substituted Phenols with Water and Chloride Ion

Por Jorgensen, William L., Jensen, Kasper P., Alexandrova, Anastassia N.
Publicado em 2007

Metavanadate at the active site of the phosphatase VHZ

Por Kuznetsov, Vyacheslav I., Alexandrova, Anastassia N., Hengge, Alvan C.
Publicado em 2012

Catalytic Mechanism and Performance of Computationally Designed Enzymes for Kemp Elimination

Por Alexandrova, Anastassia N., Röthlisberger, Daniela, Baker, David, Jorgensen, William L.
Publicado em 2008

Quantified electrostatic preorganization in enzymes using the geometry of the electron charge density

Por Morgenstern, Amanda, Jaszai, Matthew, Eberhart, Mark E., Alexandrova, Anastassia N.
Publicado no Chem Sci (2017)

Hybrid Dynamics Simulation Engine for Metalloproteins

Por Sparta, Manuel, Shirvanyants, David, Ding, Feng, Dokholyan, Nikolay V., Alexandrova, Anastassia N.
Publicado em 2012

Cu,Zn-Superoxide Dismutase without Zn is Folded but Catalytically Inactive

Por Nedd, Sean, Redler, Rachel L., Proctor, Elizabeth A., Dokholyan, Nikolay V., Alexandrova, Anastassia N.
Publicado no J Mol Biol (2014)

Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites

Por Moise, Gwendolyn, Gallup, Nathan M., Alexandrova, Anastassia N., Hengge, Alvan C., Johnson, Sean J.
Publicado no Biochemistry (2015)

Molecular basis for nanoscopic membrane curvature generation from quantum mechanical models and synthetic transporter sequences

Por Schmidt, Nathan W., Lis, Michael, Zhao, Kun, Lai, Ghee Hwee, Alexandrova, Anastassia, Tew, Gregory N., Wong, Gerard C. L.
Publicado em 2012

Selected AB(4) (2−/−) (A = C, Si, Ge; B = Al, Ga, In) ions: a battle between covalency and aromaticity, and prediction of square planar Si in SiIn(4) (2−/−)

Por Alexandrova, Anastassia N., Nayhouse, Michael J., Huynh, Mioy T., Kuo, Jonathan L., Melkonian, Arek V., Chavez, Gerardo, Hernando, Nina M., Kowal, Matthew D., Liu, Chi-Ping
Publicado em 2012

Structure-Guided Development of Deoxycytidine Kinase Inhibitors with Nanomolar Affinity and Improved Metabolic Stability

Por Nomme, Julian, Li, Zheng, Gipson, Raymond M., Wang, Jue, Armijo, Amanda L., Le, Thuc, Poddar, Soumya, Smith, Tony, Santarsiero, Bernard D., Nguyen, Hien-Anh, Czernin, Johannes, Alexandrova, Anastassia N., Jung, Michael E., Radu, Caius G., Lavie, Arnon
Publicado no J Med Chem (2014)

Development of new deoxycytidine kinase inhibitors and non-invasive in vivo evaluation using Positron Emission Tomography

Por Murphy, Jennifer M., Armijo, Amanda L., Nomme, Julian, Lee, Chi Hang, Smith, Quentin A., Li, Zheng, Campbell, Dean O., Liao, Hsiang-I, Nathanson, David A., Austin, Wayne R., Lee, Jason T., Darvish, Ryan, Wei, Liu, Wang, Jue, Su, Ying, Damoiseaux, Robert, Sadeghi, Saman, Phelps, Michael E., Herschman, Harvey R., Czernin, Johannes, Alexandrova, Anastassia N., Jung, Michael E., Lavie, Arnon, Radu, Caius G.
Publicado em 2013