GRP78 Promotes Cardiomyocyte Growth through Activation of GATA4

Autor Zhang, Guangyu, Wang, Xiaoding, Bi, Xukun, Li, Chao, Deng, Yingfeng, Al-Hashimi, Ali A., Luo, Xiang, Gillette, Thomas G., Austin, Richard C., Wang, Yanggan, Wang, Zhao V.
Vydáno v Hypertension (2019)

Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained

Autor Lebeau, Paul, Platko, Khrystyna, Al-Hashimi, Ali A., Byun, Jae Hyun, Lhoták, Šárka, Holzapfel, Nicholas, Gyulay, Gabriel, Igdoura, Suleiman A., Cool, David R., Trigatti, Bernardo, Seidah, Nabil G., Austin, Richard C.
Vydáno v J Biol Chem (2018)

Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores

Autor Al-Hashimi, Ali A., Caldwell, Jennifer, Gonzalez-Gronow, Mario, Pizzo, Salvatore V., Aboumrad, Danya, Pozza, Lindsay, Al-Bayati, Hiam, Weitz, Jeffrey I., Stafford, Alan, Chan, Howard, Kapoor, Anil, Jacobsen, Donald W., Dickhout, Jeffrey G., Austin, Richard C.
Vydáno 2010

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

Autor Al-Hashimi, Ali A., Caldwell, Jennifer, Gonzalez-Gronow, Mario, Pizzo, Salvatore V., Aboumrad, Danya, Pozza, Lindsay, Al-Bayati, Hiam, Weitz, Jeffrey I., Stafford, Alan, Chan, Howard, Kapoor, Anil, Jacobsen, Donald W., Dickhout, Jeffrey G., Austin, Richard C.
Vydáno v J Biol Chem (2015)

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

Autor Lebeau, Paul F., Byun, Jae Hyun, Platko, Khrystyna, Al-Hashimi, Ali A., Lhoták, Šárka, MacDonald, Melissa E., Mejia-Benitez, Aurora, Prat, Annik, Igdoura, Suleiman A., Trigatti, Bernardo, Maclean, Kenneth N., Seidah, Nabil G., Austin, Richard C.
Vydáno v JHEP Rep (2019)

Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions

Autor Crane, Elizabeth D., Al-Hashimi, Ali A., Chen, Jack, Lynn, Edward G., Won, Kevin Doyoon, Lhoták, Šárka, Naeim, Magda, Platko, Khrystyna, Lebeau, Paul, Byun, Jae Hyun, Shayegan, Bobby, Krepinsky, Joan C., Rayner, Katey J., Marchiò, Serena, Pasqualini, Renata, Arap, Wadih, Austin, Richard C.
Vydáno v JCI Insight (2018)

The loss-of-function PCSK9(Q152H) variant increases ER chaperones GRP78 and GRP94 and protects against liver injury

Autor Lebeau, Paul F., Wassef, Hanny, Byun, Jae Hyun, Platko, Khrystyna, Ason, Brandon, Jackson, Simon, Dobroff, Joshua, Shetterly, Susan, Richards, William G., Al-Hashimi, Ali A., Won, Kevin Doyoon, Mbikay, Majambu, Prat, Annik, Tang, An, Paré, Guillaume, Pasqualini, Renata, Seidah, Nabil G., Arap, Wadih, Chrétien, Michel, Austin, Richard C.
Vydáno v J Clin Invest (2021)

Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor

Autor Al-Hashimi, Ali A., Lebeau, Paul, Majeed, Fadwa, Polena, Enio, Lhotak, Šárka, Collins, Celeste A. F., Pinthus, Jehonathan H., Gonzalez-Gronow, Mario, Hoogenes, Jen, Pizzo, Salvatore V., Crowther, Mark, Kapoor, Anil, Rak, Janusz, Gyulay, Gabriel, D'Angelo, Sara, Marchiò, Serena, Pasqualini, Renata, Arap, Wadih, Shayegan, Bobby, Austin, Richard C.
Vydáno v J Biol Chem (2017)