Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor

Tumor cells display on their surface several molecular chaperones that normally reside in the endoplasmic reticulum. Because this display is unique to cancer cells, these chaperones are attractive targets for drug development. Previous epitope-mapping of autoantibodies (AutoAbs) from prostate cancer...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Al-Hashimi, Ali A., Lebeau, Paul, Majeed, Fadwa, Polena, Enio, Lhotak, Šárka, Collins, Celeste A. F., Pinthus, Jehonathan H., Gonzalez-Gronow, Mario, Hoogenes, Jen, Pizzo, Salvatore V., Crowther, Mark, Kapoor, Anil, Rak, Janusz, Gyulay, Gabriel, D'Angelo, Sara, Marchiò, Serena, Pasqualini, Renata, Arap, Wadih, Shayegan, Bobby, Austin, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743090/
https://ncbi.nlm.nih.gov/pubmed/29066620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.799908
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