Runx2-Smad signaling impacts the progression of tumor-induced bone disease

Por Zhang, Xuhui, Akech, Jacqueline, Browne, Gillian, Russell, Stacey, Wixted, John J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Publicado no Int J Cancer (2014)

Targeting of Runx2 by miRNA-135 and miRNA-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease

Por Taipaleenmäki, Hanna, Browne, Gillian, Akech, Jacqueline, Zustin, Jozef, van Wijnen, Andre J., Stein, Janet L., Hesse, Eric, Stein, Gary S., Lian, Jane B.
Publicado no Cancer Res (2015)

Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1

Por Zhang, Xuhui, Wu, Hai, Dobson, Jason R., Browne, Gillian, Hong, Deli, Akech, Jacqueline, Languino, Lucia R., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Publicado no J Cell Biochem (2015)

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice

Por Farina, Nicholas H., Zingiryan, Areg, Akech, Jacqueline A., Callahan, Cody J., Lu, Huimin, Stein, Janet L., Languino, Lucia R., Stein, Gary S., Lian, Jane B.
Publicado no Oncotarget (2016)

Genomic Promoter Occupancy of Runt-related Transcription Factor RUNX2 in Osteosarcoma Cells Identifies Genes Involved in Cell Adhesion and Motility

Por van der Deen, Margaretha, Akech, Jacqueline, Lapointe, David, Gupta, Sneha, Young, Daniel W., Montecino, Martin A., Galindo, Mario, Lian, Jane B., Stein, Janet L., Stein, Gary S., van Wijnen, Andre J.
Publicado em 2012

Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression

Por Pratap, Jitesh, Imbalzano, Karen M., Underwood, Jean M., Cohet, Nathalie, Gokul, Karthiga, Akech, Jacqueline, van Wijnen, Andre J., Stein, Janet L., Imbalzano, Anthony N., Nickerson, Jeffrey A., Lian, Jane B., Stein, Gary S.
Publicado em 2009

Runx2 Association with Progression of Prostate Cancer in Patients: Mechanisms Mediating Bone Osteolysis and Osteoblastic Metastatic Lesions

Por Akech, Jacqueline, Wixted, John J., Bedard, Krystin, van der Deen, Margaretha, Hussain, Sadiq, Guise, Theresa A., van Wijnen, Andre J., Stein, Janet L., Languino, Lucia R., Altieri, Dario C., Pratap, Jitesh, Keller, Evan, Stein, Gary S., Lian, Jane B.
Publicado em 2009

The Histone Deacetylase Inhibitor, Vorinostat, Reduces Tumor Growth at the Metastatic Bone Site and Associated Osteolysis, but Promotes Normal Bone Loss

Por Pratap, Jitesh, Akech, Jacqueline, Wixted, John J., Szabo, Gabriela, Hussain, Sadiq, McGee-Lawrence, Meghan E., Li, Xiaodong, Bedard, Krystin, Dhillon, Robinder J., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Westendorf, Jennifer J., Lian, Jane B.
Publicado em 2010

The αvβ6 integrin promotes an osteolytic program through upregulation of MMP2

Por Dutta, Anindita, Li, Jing, Lu, Huimin, Akech, Jacqueline, Pratap, Jitesh, Wang, Tao, Zerlanko, Brad J., FitzGerald, Thomas J., Jiang, Zhong, Birbe, Ruth, Wixted, John, Violette, Shelia M., Stein, Janet L., Stein, Gary S., Lian, Jane B., Languino, Lucia R.
Publicado em 2014

The SWI/SNF ATPases are Required for Triple Negative Breast Cancer Cell Proliferation

Por Wu, Qiong, Madany, Pasil, Akech, Jacqueline, Dobson, Jason R., Douthwright, Stephen, Browne, Gillian, Colby, Jennifer L., Winter, Georg E., Bradner, James E., Pratap, Jitesh, Sluder, Greenfield, Bhargava, Rohit, Chiosea, Simion, van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B., Nickerson, Jeffrey A., Imbalzano, Anthony N.
Publicado no J Cell Physiol (2015)