Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation

Por Akagi, Tsuyoshi, Sasai, Ken, Hanafusa, Hidesaburo
Publicado em 2003

v-Crk activates the phosphoinositide 3-kinase/AKT pathway in transformation

Por Akagi, Tsuyoshi, Shishido, Tomoyuki, Murata, Kazutaka, Hanafusa, Hidesaburo
Publicado em 2000

v-Crk Activates the Phosphoinositide 3-Kinase/AKT Pathway by Utilizing Focal Adhesion Kinase and H-Ras

Por Akagi, Tsuyoshi, Murata, Kazutaka, Shishido, Tomoyuki, Hanafusa, Hidesaburo
Publicado em 2002

CrkII regulates focal adhesion kinase activation by making a complex with Crk-associated substrate, p130(Cas)

Por Iwahara, Toshinori, Akagi, Tsuyoshi, Fujitsuka, Yuki, Hanafusa, Hidesaburo
Publicado em 2004

PTEN Induces Cell Cycle Arrest by Decreasing the Level and Nuclear Localization of Cyclin D1

Por Radu, Aurelian, Neubauer, Valerie, Akagi, Tsuyoshi, Hanafusa, Hidesaburo, Georgescu, Maria-Magdalena
Publicado em 2003

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

Por Georgescu, Maria-Magdalena, Kirsch, Kathrin H., Akagi, Tsuyoshi, Shishido, Tomoyuki, Hanafusa, Hidesaburo
Publicado em 1999

O(6)-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies

Por Sasai, Ken, Akagi, Tsuyoshi, Aoyanagi, Eiko, Tabu, Kouichi, Kaneko, Sadao, Tanaka, Shinya
Publicado em 2007

The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation

Por Shishido, Tomoyuki, Akagi, Tsuyoshi, Ouchi, Toru, Georgescu, Maria-Magdalena, Langdon, Wallace Y., Hanafusa, Hidesaburo
Publicado em 2000

Functional development of Src tyrosine kinases during evolution from a unicellular ancestor to multicellular animals

Por Segawa, Yuko, Suga, Hiroshi, Iwabe, Naoyuki, Oneyama, Chitose, Akagi, Tsuyoshi, Miyata, Takashi, Okada, Masato
Publicado em 2006

FRA1 is a determinant for the difference in RAS-induced transformation between human and rat fibroblasts

Por Kakumoto, Kyoko, Sasai, Ken, Sukezane, Taiko, Oneyama, Chitose, Ishimaru, Satoshi, Shibutani, Kana, Mizushima, Hiroto, Mekada, Eisuke, Hanafusa, Hidesaburo, Akagi, Tsuyoshi
Publicado em 2006

Engineering cancer stem-like cells from normal human lung epithelial cells

Por Sasai, Ken, Takao-Rikitsu, Etsuko, Sukezane, Taiko, Yanagita, Emmy, Nakagawa, Harumi, Itoh-Yagi, Machiko, Izumi, Yukina, Itoh, Tomoo, Akagi, Tsuyoshi
Publicado no PLoS One (2017)

mDia1 Targets v-Src to the Cell Periphery and Facilitates Cell Transformation, Tumorigenesis, and Invasion

Por Tanji, Masahiro, Ishizaki, Toshimasa, Ebrahimi, Saman, Tsuboguchi, Yuko, Sukezane, Taiko, Akagi, Tsuyoshi, Frame, Margaret C., Hashimoto, Nobuo, Miyamoto, Susumu, Narumiya, Shuh
Publicado em 2010

Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5α/β

Por Hotta, Azusa, Kawakatsu, Tomomi, Nakatani, Tomoya, Sato, Toshitaka, Matsui, Chiyuki, Sukezane, Taiko, Akagi, Tsuyoshi, Hamaji, Tomoko, Grigoriev, Ilya, Akhmanova, Anna, Takai, Yoshimi, Mimori-Kiyosue, Yuko
Publicado em 2010

Antitumor effects of eribulin depend on modulation of the tumor microenvironment by vascular remodeling in mouse models

Por Ito, Ken, Hamamichi, Shusei, Abe, Takanori, Akagi, Tsuyoshi, Shirota, Hiroshi, Kawano, Satoshi, Asano, Makoto, Asano, Osamu, Yokoi, Akira, Matsui, Junji, Umeda, Izumi O., Fujii, Hirofumi
Publicado no Cancer Sci (2017)