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v-Crk Activates the Phosphoinositide 3-Kinase/AKT Pathway by Utilizing Focal Adhesion Kinase and H-Ras

v-Crk, an oncogene product of avian sarcoma virus CT10, efficiently transforms chicken embryo fibroblasts (CEF). We have recently reported that constitutive activation of the phosphoinositide 3-kinase (PI3K)/AKT pathway plays a critical role in the v-Crk-induced transformation of CEF. In the present...

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Hlavní autoři: Akagi, Tsuyoshi, Murata, Kazutaka, Shishido, Tomoyuki, Hanafusa, Hidesaburo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC139810/
https://ncbi.nlm.nih.gov/pubmed/12242282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7015-7023.2002
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