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v-Crk activates the phosphoinositide 3-kinase/AKT pathway in transformation

v-Crk induces cellular tyrosine phosphorylation and transformation of chicken embryo fibroblasts (CEF). We studied the molecular mechanism of the v-Crk-induced transformation. Experiments with Src homology (SH)2 and SH3 domain mutants revealed that the induction of tyrosine phosphorylation of cellul...

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Bibliografiset tiedot
Päätekijät: Akagi, Tsuyoshi, Shishido, Tomoyuki, Murata, Kazutaka, Hanafusa, Hidesaburo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC16538/
https://ncbi.nlm.nih.gov/pubmed/10852971
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