mDia1 Targets v-Src to the Cell Periphery and Facilitates Cell Transformation, Tumorigenesis, and Invasion

The small GTPase Rho regulates cell morphogenesis through remodeling of the actin cytoskeleton. While Rho is overexpressed in many clinical cancers, the role of Rho signaling in oncogenesis remains unknown. mDia1 is a Rho effector producing straight actin filaments. Here we transduced mouse embryoni...

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Detalhes bibliográficos
Main Authors: Tanji, Masahiro, Ishizaki, Toshimasa, Ebrahimi, Saman, Tsuboguchi, Yuko, Sukezane, Taiko, Akagi, Tsuyoshi, Frame, Margaret C., Hashimoto, Nobuo, Miyamoto, Susumu, Narumiya, Shuh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950524/
https://ncbi.nlm.nih.gov/pubmed/20679479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00197-10
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