The Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells through Mobilizing Apc and c-Src

Directed cell migration requires cell polarization and adhesion turnover, in which the actin cytoskeleton and microtubules work critically. The Rho GTPases induce specific types of actin cytoskeleton and regulate microtubule dynamics. In migrating cells, Cdc42 regulates cell polarity and Rac works i...

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Main Authors: Yamana, Norikazu, Arakawa, Yoshiki, Nishino, Tomohiro, Kurokawa, Kazuo, Tanji, Masahiro, Itoh, Reina E., Monypenny, James, Ishizaki, Toshimasa, Bito, Haruhiko, Nozaki, Kazuhiko, Hashimoto, Nobuo, Matsuda, Michiyuki, Narumiya, Shuh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592856/
https://ncbi.nlm.nih.gov/pubmed/16943426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00283-06
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