Control of axon elongation via an SDF-1α/Rho/mDia pathway in cultured cerebellar granule neurons

Rho–GTPase has been implicated in axon outgrowth. However, not all of the critical steps controlled by Rho have been well characterized. Using cultured cerebellar granule neurons, we show here that stromal cell–derived factor (SDF)-1α, a neural chemokine, is a physiological ligand that can turn on t...

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Main Authors: Arakawa, Yoshiki, Bito, Haruhiko, Furuyashiki, Tomoyuki, Tsuji, Takahiro, Takemoto-Kimura, Sayaka, Kimura, Kazuhiro, Nozaki, Kazuhiko, Hashimoto, Nobuo, Narumiya, Shuh
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172896/
https://ncbi.nlm.nih.gov/pubmed/12707308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210149
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