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ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts
The small GTPase Rho acts on two effectors, ROCK and mDia1, and induces stress fibers and focal adhesions. However, how ROCK and mDia1 individually regulate signals and dynamics of these structures remains unknown. We stimulated serum-starved Swiss 3T3 fibroblasts with LPA and compared the effects o...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173402/ https://ncbi.nlm.nih.gov/pubmed/12021256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112107 |
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