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Antitumor effects of eribulin depend on modulation of the tumor microenvironment by vascular remodeling in mouse models

We previously reported that eribulin mesylate (eribulin), a tubulin‐binding drug (TBD), could remodel tumor vasculature (i.e. increase tumor vessels and perfusion) in human breast cancer xenograft models. However, the role of this vascular remodeling in antitumor effects is not fully understood. Her...

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Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Ito, Ken, Hamamichi, Shusei, Abe, Takanori, Akagi, Tsuyoshi, Shirota, Hiroshi, Kawano, Satoshi, Asano, Makoto, Asano, Osamu, Yokoi, Akira, Matsui, Junji, Umeda, Izumi O., Fujii, Hirofumi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665763/
https://ncbi.nlm.nih.gov/pubmed/28869796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13392
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