Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models

Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B and an inhibitor of microtubule dynamics. Some tubulin-binding drugs are known to have antivascular (antiangiogenesis or vascular-disrupting) activities that can target abnormal tumor vesse...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Funahashi, Yasuhiro, Okamoto, Kiyoshi, Adachi, Yusuke, Semba, Taro, Uesugi, Mai, Ozawa, Yoichi, Tohyama, Osamu, Uehara, Taisuke, Kimura, Takayuki, Watanabe, Hideki, Asano, Makoto, Kawano, Satoshi, Tizon, Xavier, McCracken, Paul J, Matsui, Junji, Aoshima, Ken, Nomoto, Kenichi, Oda, Yoshiya
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462349/
https://ncbi.nlm.nih.gov/pubmed/25060424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12488
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