Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABA(A) receptor subtype

Por Ralvenius, William T., Benke, Dietmar, Acuña, Mario A., Rudolph, Uwe, Zeilhofer, Hanns Ulrich
Publicado no Nat Commun (2015)

Effects of N-glycosylation of the human cation channel TRPA1 on agonist-sensitivity

Por Egan, Timothy J., Acuña, Mario A., Zenobi-Wong, Marcy, Zeilhofer, Hanns Ulrich, Urech, David
Publicado no Biosci Rep (2016)

Endoplasmic Reticulum-associated Degradation Controls Cell Surface Expression of γ-Aminobutyric Acid, Type B Receptors

Por Zemoura, Khaled, Schenkel, Marisa, Acuña, Mario A., Yévenes, Gonzalo E., Ulrich Zeilhofer, Hanns, Benke, Dietmar
Publicado em 2013

Ischemia-like Oxygen and Glucose Deprivation Mediates Down-regulation of Cell Surface γ-Aminobutyric Acid(B) Receptors via the Endoplasmic Reticulum (ER) Stress-induced Transcripti...

Por Maier, Patrick J., Zemoura, Khaled, Acuña, Mario A., Yévenes, Gonzalo E., Zeilhofer, Hanns Ulrich, Benke, Dietmar
Publicado em 2014

The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia

Por Ralvenius, William T., Acuña, Mario A., Benke, Dietmar, Matthey, Alain, Daali, Youssef, Rudolph, Uwe, Desmeules, Jules, Zeilhofer, Hanns Ulrich, Besson, Marie
Publicado no Neuropharmacology (2016)

Phosphorylation state–dependent modulation of spinal glycine receptors alleviates inflammatory pain

Por Acuña, Mario A., Yévenes, Gonzalo E., Ralvenius, William T., Benke, Dietmar, Di Lio, Alessandra, Lara, Cesar O., Muñoz, Braulio, Burgos, Carlos F., Moraga-Cid, Gustavo, Corringer, Pierre-Jean, Zeilhofer, Hanns Ulrich
Publicado no J Clin Invest (2016)

Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA(A) receptors

Por Ralvenius, William T., Neumann, Elena, Pagani, Martina, Acuña, Mario A., Wildner, Hendrik, Benke, Dietmar, Fischer, Nina, Rostaher, Ana, Schwager, Simon, Detmar, Michael, Frauenknecht, Katrin, Aguzzi, Adriano, Hubbs, Jed Lee, Rudolph, Uwe, Favrot, Claude, Zeilhofer, Hanns Ulrich
Publicado no Nat Commun (2018)

Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission

Por Ghosh, Himanish, Auguadri, Luca, Battaglia, Sereina, Simone Thirouin, Zahra, Zemoura, Khaled, Messner, Simon, Acuña, Mario A., Wildner, Hendrik, Yévenes, Gonzalo E., Dieter, Andrea, Kawasaki, Hiroshi, O. Hottiger, Michael, Zeilhofer, Hanns Ulrich, Fritschy, Jean-Marc, Tyagarajan, Shiva K.
Publicado no Nat Commun (2016)

Further corroboration of distinct functional features in SCN2A variants causing intellectual disability or epileptic phenotypes

Por Begemann, Anaïs, Acuña, Mario A., Zweier, Markus, Vincent, Marie, Steindl, Katharina, Bachmann-Gagescu, Ruxandra, Hackenberg, Annette, Abela, Lucia, Plecko, Barbara, Kroell-Seger, Judith, Baumer, Alessandra, Yamakawa, Kazuhiro, Inoue, Yushi, Asadollahi, Reza, Sticht, Heinrich, Zeilhofer, Hanns Ulrich, Rauch, Anita
Publicado no Mol Med (2019)