Ischemia-like Oxygen and Glucose Deprivation Mediates Down-regulation of Cell Surface γ-Aminobutyric Acid(B) Receptors via the Endoplasmic Reticulum (ER) Stress-induced Transcription Factor CCAAT/Enhancer-binding Protein (C/EBP)-homologous Protein (CHOP)

Cerebral ischemia frequently leads to long-term disability and death. Excitotoxicity is believed to be the main cause for ischemia-induced neuronal death. Although a role of glutamate receptors in this process has been firmly established, the contribution of metabotropic GABA(B) receptors, which con...

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Detalhes bibliográficos
Main Authors: Maier, Patrick J., Zemoura, Khaled, Acuña, Mario A., Yévenes, Gonzalo E., Zeilhofer, Hanns Ulrich, Benke, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007477/
https://ncbi.nlm.nih.gov/pubmed/24668805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550517
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