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Proteasomal Degradation of γ-Aminobutyric Acid(B) Receptors Is Mediated by the Interaction of the GABA(B2) C Terminus with the Proteasomal ATPase Rtp6 and Regulated by Neuronal Activity
Regulation of cell surface expression of neurotransmitter receptors is crucial for determining synaptic strength and plasticity, but the underlying mechanisms are not well understood. We previously showed that proteasomal degradation of GABA(B) receptors via the endoplasmic reticulum (ER)-associated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953284/ https://ncbi.nlm.nih.gov/pubmed/24482233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541987 |
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