Endoplasmic Reticulum-associated Degradation Controls Cell Surface Expression of γ-Aminobutyric Acid, Type B Receptors

Metabotropic GABA(B) receptors are crucial for controlling the excitability of neurons by mediating slow inhibition in the CNS. The strength of receptor signaling depends on the number of cell surface receptors, which is thought to be regulated by trafficking and degradation mechanisms. Although the...

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Detalhes bibliográficos
Main Authors: Zemoura, Khaled, Schenkel, Marisa, Acuña, Mario A., Yévenes, Gonzalo E., Ulrich Zeilhofer, Hanns, Benke, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843101/
https://ncbi.nlm.nih.gov/pubmed/24114844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514745
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