Phosphorylation state–dependent modulation of spinal glycine receptors alleviates inflammatory pain

Diminished inhibitory neurotransmission in the superficial dorsal horn of the spinal cord is thought to contribute to chronic pain. In inflammatory pain, reductions in synaptic inhibition occur partially through prostaglandin E(2)- (PGE(2)-) and PKA-dependent phosphorylation of a specific subtype of...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Acuña, Mario A., Yévenes, Gonzalo E., Ralvenius, William T., Benke, Dietmar, Di Lio, Alessandra, Lara, Cesar O., Muñoz, Braulio, Burgos, Carlos F., Moraga-Cid, Gustavo, Corringer, Pierre-Jean, Zeilhofer, Hanns Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922714/
https://ncbi.nlm.nih.gov/pubmed/27270175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83817
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