Phosphorylation state–dependent modulation of spinal glycine receptors alleviates inflammatory pain

Diminished inhibitory neurotransmission in the superficial dorsal horn of the spinal cord is thought to contribute to chronic pain. In inflammatory pain, reductions in synaptic inhibition occur partially through prostaglandin E(2)- (PGE(2)-) and PKA-dependent phosphorylation of a specific subtype of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Acuña, Mario A., Yévenes, Gonzalo E., Ralvenius, William T., Benke, Dietmar, Di Lio, Alessandra, Lara, Cesar O., Muñoz, Braulio, Burgos, Carlos F., Moraga-Cid, Gustavo, Corringer, Pierre-Jean, Zeilhofer, Hanns Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922714/
https://ncbi.nlm.nih.gov/pubmed/27270175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83817
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