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Molecular Sites for the Positive Allosteric Modulation of Glycine Receptors by Endocannabinoids

Glycine receptors (GlyRs) are transmitter-gated anion channels of the Cys-loop superfamily which mediate synaptic inhibition at spinal and selected supraspinal sites. Although they serve pivotal functions in motor control and sensory processing, they have yet to be exploited as drug targets partly b...

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Bibliographic Details
Main Authors: Yévenes, Gonzalo E., Zeilhofer, Hanns Ulrich
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162021/
https://ncbi.nlm.nih.gov/pubmed/21901142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023886
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