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Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA(A) receptors
Chronic itch is a highly debilitating condition affecting about 10% of the general population. The relay of itch signals is under tight control by inhibitory circuits of the spinal dorsal horn, which may offer a hitherto unexploited therapeutic opportunity. Here, we found that specific pharmacologic...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089996/ https://ncbi.nlm.nih.gov/pubmed/30104684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05709-0 |
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