A clickable psoralen to directly quantify DNA interstrand crosslinking and repair

Bằng Evison, Benjamin J., Actis, Marcelo L., Fujii, Naoaki
Xuất bản năm Bioorg Med Chem (2016)

A novel assay revealed that ribonucleotide reductase is functionally important for interstrand DNA crosslink repair

Bằng Fujii, Naoaki, Evison, Benjamin J., Actis, Marcelo L., Inoue, Akira
Xuất bản năm Bioorg Med Chem (2015)

A site-selective, irreversible inhibitor of the DNA replication auxiliary factor proliferating cell nuclear antigen (PCNA)

Bằng Evison, Benjamin J., Actis, Marcelo L., Wu, Zhexiang, Shao, Youming, Heath, Richard J., Yang, Lei, Fujii, Naoaki
Xuất bản năm Bioorg Med Chem (2014)

Small-molecules that bind to the ubiquitin-binding motif of REV1 inhibit REV1 interaction with K164-monoubiquitinated PCNA and suppress DNA damage tolerance

Bằng Vanarotti, Murugendra, Evison, Benjamin J., Actis, Marcelo L., Inoue, Akira, McDonald, Ezelle T., Shao, Youming, Heath, Richard J., Fujii, Naoaki
Xuất bản năm Bioorg Med Chem (2018)

A Small Molecule Inhibitor of Monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) Inhibits Repair of Interstrand DNA Cross-link, Enhances DNA Double Strand Break, and Sensi...

Bằng Inoue, Akira, Kikuchi, Sotaro, Hishiki, Asami, Shao, Youming, Heath, Richard, Evison, Benjamin J., Actis, Marcelo, Canman, Christine E., Hashimoto, Hiroshi, Fujii, Naoaki
Được phát hành 2014

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction

Bằng Actis, Marcelo L., Ambaye, Nigus D., Evison, Benjamin J., Shao, Youming, Vanarotti, Murugendra, Inoue, Akira, McDonald, Ezelle T., Kikuchi, Sotaro, Heath, Richard, Hara, Kodai, Hashimoto, Hiroshi, Fujii, Naoaki
Xuất bản năm Bioorg Med Chem (2016)

Capturing the direct binding of CFTR correctors to CFTR using click chemistry

Bằng Sinha, Chandrima, Zhang, Weiqiang, Moon, Chang Suk, Actis, Marcelo, Yarlagadda, Sunitha, Arora, Kavisha, Woodroofe, Koryse, Clancy, John P., Lin, Songbai, Ziady, Assem G., Frizzell, Raymond, Fujii, Naoaki, Naren, Anjaparavanda P.
Xuất bản năm Chembiochem (2015)

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

Bằng Kamadurai, Hari B, Qiu, Yu, Deng, Alan, Harrison, Joseph S, MacDonald, Chris, Actis, Marcelo, Rodrigues, Patrick, Miller, Darcie J, Souphron, Judith, Lewis, Steven M, Kurinov, Igor, Fujii, Naoaki, Hammel, Michal, Piper, Robert, Kuhlman, Brian, Schulman, Brenda A
Được phát hành 2013

RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex

Bằng Brown, Nicholas G., VanderLinden, Ryan, Watson, Edmond R., Qiao, Renping, Grace, Christy R. R., Yamaguchi, Masaya, Weissmann, Florian, Frye, Jeremiah J., Dube, Prakash, Ei Cho, Shein, Actis, Marcelo L., Rodrigues, Patrick, Fujii, Naoaki, Peters, Jan-Michael, Stark, Holger, Schulman, Brenda A.
Xuất bản năm Proc Natl Acad Sci U S A (2015)

NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells

Bằng Paugh, Steven W., Bonten, Erik J., Savic, Daniel, Ramsey, Laura B., Thierfelder, William E., Gurung, Prajwal, Malireddi, R. K. Subbarao, Actis, Marcelo, Mayasundari, Anand, Min, Jaeki, Coss, David R., Laudermilk, Lucas T., Panetta, John C., McCorkle, J. Robert, Fan, Yiping, Crews, Kristine R., Stocco, Gabriele, Wilkinson, Mark R., Ferreira, Antonio M., Cheng, Cheng, Yang, Wenjian, Karol, Seth E., Fernandez, Christian A., Diouf, Barthelemy, Smith, Colton, Hicks, J. Kevin, Zanut, Alessandra, Giordanengo, Audrey, Crona, Daniel, Bianchi, Joy J., Holmfeldt, Linda, Mullighan, Charles G., den Boer, Monique L., Pieters, Rob, Jeha, Sima, Dunwell, Thomas L., Latif, Farida, Bhojwani, Deepa, Carroll, William L., Pui, Ching-Hon, Myers, Richard M., Guy, R. Kiplin, Kanneganti, Thirumala-Devi, Relling, Mary V., Evans, William E.
Xuất bản năm Nat Genet (2015)