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A clickable psoralen to directly quantify DNA interstrand crosslinking and repair
DNA interstrand crosslinks (ICLs) represent physical obstacles to advancing replication forks and transcription complexes. A range of ICL-inducing agents have successfully been incorporated into cancer therapeutics. While studies have adopted UVA-activated psoralens as model ICL-inducing agents for...
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| Publicado en: | Bioorg Med Chem |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762217/ https://ncbi.nlm.nih.gov/pubmed/26833244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.01.032 |
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